The protective effect of fenretinide against allergic asthma
نویسندگان
چکیده
منابع مشابه
The protective effect of fenretinide against allergic asthma
Objective/purpose Fenretinide [N-4-hydroxyphenyl, 4HPR] is a synthetic retinoid derived from vitamin A with pro-apoptotic and anti-inflammatory properties. Studies have shown that at high concentrations fenretinide is an effective antineoplastic agent, regulating cell growth and differentiation. We have recently demonstrated that fenretinide, at doses 5-10× lower than for cancer treatment, has ...
متن کاملInduction of experimental allergic asthma in cat
19 cats were nper-sensitized to allergic asthma by receiving a concomitant spray ang injection of ovalbumin (10% fresh egg-white in normal saline) every other days for four weeks.then animals were anesthetized and left femoral artery cannulation performed to record atrerial pressure and take blood samples.left femoral vein was cannulated to infuse nutritional fluids and grugs as needed.trachea ...
متن کاملGeneral overview of fungal allergic asthma
Asthma is a complicated disorder, whose prevalence has increased over the past few decades.Asthma is characterized by infiltration of inflammatory leukocytes along with enhancedproinflammatory cytokines and chemokines. Fungi are now far more widely being considered as thedominant extrinsic trigger for asthma. Fungi are linked to the severity of asthma in many ways. Somedifferences between studi...
متن کاملNrf2 Is a Protective Factor against Oxidative Stresses Induced by Diesel Exhaust Particle in Allergic Asthma
Epidemiological studies have shown that air pollutants, such as diesel exhaust particle (DEP), are implicated in the increased incidence of allergic airway disorders. In vitro studies of molecular mechanisms have focused on the role of reactive oxygen species generated directly and indirectly by the exposure to DEP. Antioxidants effectively reduce the allergic inflammatory effects induced by DE...
متن کاملthe effect of taftan pozzolan on the compressive strength of concrete in the environmental conditions of oman sea (chabahar port)
cement is an essential ingredient in the concrete buildings. for production of cement considerable amount of fossil fuel and electrical energy is consumed. on the other hand for generating one tone of portland cement, nearly one ton of carbon dioxide is released. it shows that 7 percent of the total released carbon dioxide in the world relates to the cement industry. considering ecological issu...
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Allergy, Asthma & Clinical Immunology
سال: 2010
ISSN: 1710-1492
DOI: 10.1186/1710-1492-6-s3-p18